Associate Director, Obesity Metabolism and Muscle Disease

Role Summary

Associate Director, Obesity Metabolism and Muscle Disease. Regeneron seeks a leader in skeletal muscle physiology and biology to head its research and therapeutic development team. This group uses molecular cell biology, genetic, and transcriptomic profiling techniques, as well as genetic animal models to understand muscle physiology and pathophysiology at the cellular and molecular level, with the goal of identifying new therapeutic and diagnostic platforms for muscle degenerative diseases and inflammatory conditions.

Responsibilities

• Establish the strategic framework for muscle biology research, including identification of new therapeutic targets‚Äîparticularly for genetic diseases‚Äîand incorporation of emerging technologies and scientific developments into the research pipeline.
• Design, coordinate, and supervise complex in vitro and in vivo studies investigating muscle development, physiological and metabolic function, regeneration, and disease mechanisms.
• Guide and manage a team of scientists, research associates, and technical professionals to deliver high-caliber, rigorous, and impactful research results.
• Lead and set clear short- and long-term objectives to ensure the production of quality scientific output.
• Oversee project workflows, making critical decisions regarding project continuation, and facilitating the efficient transition of drug targets through developmental stages.
• Actively engage in cross-functional leadership meetings, contributing expertise in muscle cell biology and advocating the team‚Äôs vision.
• Promote collaboration between therapeutic areas and technology groups, fostering relationships and utilizing resources to enhance research outcomes.
• Review and authorize muscle-related documentation, including regulatory submissions, manuscripts, and contracts.

Qualifications

• Experience with cutting-edge technologies and their application to muscular disorders such as genetic targeting with siRNA, shRNA, CRISPR/Cas9, AAVs is advantageous
• Exceptional written and verbal communication skills, with the ability to articulate scientific concepts and strategic vision.
• Proven leadership, managerial, and mentorship abilities and the ability to work in a matrix environment.
• Experience in group administration, including budget and organizational management.
• Exposure to drug development or regulated activities is highly desirable.
• Strong professional network, publication record, and national/international reputation preferred.

Education

• PhD in Molecular Biology, Biomedicine, Biochemistry, Human Biology, Human Skeletal or Exercise Physiology, or a related discipline.
• Extensive cellular and molecular biology expertise in muscle biology and metabolism is desirable.
• Minimum of 5-10 years post-PhD experience and at least 2-5 years in industry or translational settings preferred.