Associate Director, Manufacturing Science and Technology

Role: Associate Director, MS&T leading process transfer, scale-up, and validation for oligonucleotide manufacturing at Arrowhead Pharmaceuticals, a leader in RNAi therapeutics. Responsibilities: oversee teams of scientists, engineers, and documentation specialists; manage GMP process validation and tech transfer activities; ensure compliance with FDA, EMA, ICH guidelines; lead troubleshooting, process optimization, and implementation of new technologies; provide mentorship and stakeholder updates. Requirements: PhD in Organic Chemistry or related field with 6+ years, MS with 10+ years, or BS with 12+ years in GMP drug development, scale-up, and manufacturing—preferably in oligonucleotides or related chemistries; strong understanding of analytical methods like HPLC-MS, UV, NMR; proven experience in process validation, GMP documentation, and technology transfer; demonstrated leadership, project management, and cross-functional collaboration skills. HighValue: GMP oligonucleotide manufacturing, process validation, technology transfer, regulated environments, cross-functional leadership, compliance with global regulatory standards. WorkSetup: not specified; likely in a hybrid or onsite facility in Wisconsin.