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Associate Director, Heme Global Business Systems

Vertex Pharmaceuticals
September 08, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
IT
Role: Associate Director, Heme CGT Business Systems, responsible for leading global system strategies for CASGEVY, a CRISPR-based autologous gene therapy for Sickle Cell Disease and beta thalassemia. Responsibilities include developing product roadmaps, collaborating with IT and regional stakeholders to implement scalable commercial tools, ensuring GxP compliance, and driving process improvements across international and US teams involved in therapy delivery. The position requires cross-functional leadership, stakeholder management, and change management expertise. Qualifications: Bachelor's degree, 8+ years in digital program delivery within regulated environments, with experience in GxP systems, digital transformation, and system integrations. Strong analytical, strategic planning, and simplification skills are essential. High-value details: focus on cell and gene therapy modality, advanced therapy medicinal product (ATMP), global scale with multi-market expansion, emphasis on commercial operations, GxP regulation, and cross-functional stakeholder engagement. Work setup: hybrid on-site in Boston, with flexible work arrangements.