Associate Director / Director, Clinical Science
Immunome, Inc.
August 21, 2026
Remote friendly (Bothell, WA)
United States
Clinical Research and Development
Position Overview:
Immunome is seeking an Associate Director / Director, Clinical Science to provide scientific leadership for clinical development programs across the oncology portfolio.
Responsibilities:
- Partner with Clinical Development leadership to define clinical strategy and contribute to integrated clinical development plans.
- Provide scientific leadership for clinical study design (Phase 1–3), including endpoints, eligibility criteria, dose/regimen rationale, and biomarker strategy.
- Serve as a key clinical development voice in program governance to enable timely, data-driven decisions balancing patient safety, scientific value, and timelines.
- Lead scientific execution of clinical studies with Clinical Operations, Data Management, Biostatistics, Clinical Pharmacology, Translational Medicine, and Safety.
- Support medical monitoring by reviewing safety data, protocol deviations, and emerging risk/benefit considerations.
- Review and interpret clinical data (safety, efficacy, PK/PD, biomarkers), generate insights, and communicate results.
- Provide oversight of CROs/vendors (central labs, imaging, biomarkers) to ensure protocol alignment and data quality.
- Collaborate with external investigators, steering committees, and key opinion leaders for execution, recruitment, and scientific communication.
- Author/review clinical protocols, amendments, investigator brochures, informed consent forms, SAPs, clinical study reports, and regulatory submissions (IND/CTA, annual reports, briefing packages).
- Contribute to responses to health authority questions; ensure GCP, regulations, and internal quality standards.
- Lead, mentor, and develop clinical scientists/contractors; drive cross-functional alignment; support scientific dissemination.
Qualifications:
- PhD, PharmD, MD, or equivalent advanced degree in life science with 5+ years clinical development experience (oncology preferred).
- Experience designing/executing oncology clinical trials (protocol development, endpoint selection, feasibility).
- Track record authoring/reviewing clinical documents and contributing to regulatory submissions/health authority interactions.
- Ability to interpret clinical/translational data (safety, efficacy, PK/PD, biomarkers) and present to diverse audiences.
- Knowledge of ICH/GCP and global clinical development regulations.
- Matrix leadership and vendor/partner management; people management a plus.
Knowledge & Skills:
- Strong clinical trial design/execution knowledge across phases; oncology/targeted therapeutics foundation.
- Expertise writing/reviewing/QC’ing protocols, ICFs, IBs, CSRs, briefing documents.
- Ability to synthesize complex datasets into scientific narratives and recommendations.
- Strong project management and cross-functional leadership; excellent written/verbal communication.
- Proactive, collaborative style with integrity, judgment, and commitment to patient safety/data quality; ability to manage multiple programs and timelines; experience mentoring.
Compensation:
- Associate Director: $177,571–$212,160
- Director: $221,245–$263,327
- Total: $177,571–$263,327 (USD)
Immunome is seeking an Associate Director / Director, Clinical Science to provide scientific leadership for clinical development programs across the oncology portfolio.
Responsibilities:
- Partner with Clinical Development leadership to define clinical strategy and contribute to integrated clinical development plans.
- Provide scientific leadership for clinical study design (Phase 1–3), including endpoints, eligibility criteria, dose/regimen rationale, and biomarker strategy.
- Serve as a key clinical development voice in program governance to enable timely, data-driven decisions balancing patient safety, scientific value, and timelines.
- Lead scientific execution of clinical studies with Clinical Operations, Data Management, Biostatistics, Clinical Pharmacology, Translational Medicine, and Safety.
- Support medical monitoring by reviewing safety data, protocol deviations, and emerging risk/benefit considerations.
- Review and interpret clinical data (safety, efficacy, PK/PD, biomarkers), generate insights, and communicate results.
- Provide oversight of CROs/vendors (central labs, imaging, biomarkers) to ensure protocol alignment and data quality.
- Collaborate with external investigators, steering committees, and key opinion leaders for execution, recruitment, and scientific communication.
- Author/review clinical protocols, amendments, investigator brochures, informed consent forms, SAPs, clinical study reports, and regulatory submissions (IND/CTA, annual reports, briefing packages).
- Contribute to responses to health authority questions; ensure GCP, regulations, and internal quality standards.
- Lead, mentor, and develop clinical scientists/contractors; drive cross-functional alignment; support scientific dissemination.
Qualifications:
- PhD, PharmD, MD, or equivalent advanced degree in life science with 5+ years clinical development experience (oncology preferred).
- Experience designing/executing oncology clinical trials (protocol development, endpoint selection, feasibility).
- Track record authoring/reviewing clinical documents and contributing to regulatory submissions/health authority interactions.
- Ability to interpret clinical/translational data (safety, efficacy, PK/PD, biomarkers) and present to diverse audiences.
- Knowledge of ICH/GCP and global clinical development regulations.
- Matrix leadership and vendor/partner management; people management a plus.
Knowledge & Skills:
- Strong clinical trial design/execution knowledge across phases; oncology/targeted therapeutics foundation.
- Expertise writing/reviewing/QC’ing protocols, ICFs, IBs, CSRs, briefing documents.
- Ability to synthesize complex datasets into scientific narratives and recommendations.
- Strong project management and cross-functional leadership; excellent written/verbal communication.
- Proactive, collaborative style with integrity, judgment, and commitment to patient safety/data quality; ability to manage multiple programs and timelines; experience mentoring.
Compensation:
- Associate Director: $177,571–$212,160
- Director: $221,245–$263,327
- Total: $177,571–$263,327 (USD)