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Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)

Amgen
September 07, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Clinical Research and Development
Role: Associate Director of Computational Biology supporting Amgen's cardiovascular, metabolic, obesity, and related therapeutic areas. Responsibilities: develop and execute biomarker analysis plans integrating multi-omics (metabolomics, genomics, proteomics, imaging, flow cytometry, spatial-omics), support clinical biomarker data interpretation for target engagement, patient stratification, and response prediction; collaborate with clinical, biometrics, and research teams for data integration and translational insights; contribute to evidence generation for precision medicine and diagnostic development; support presentations and publications. Requirements: PhD in Bioinformatics, Computational Biology, or related field with 4+ years' experience, or Master's with 7+ years', or Bachelor's with 9+ years' experience; expertise in analyzing complex biological datasets, statistical modeling, machine learning, and AI; proficiency in R and Python; familiarity with clinical biomarker platforms and diseases (cardiovascular, metabolic, inflammatory); strong communication, project management, and cross-functional collaboration skills. HighValue: focus on clinical biomarker data analysis for therapeutic development, precision medicine, and regulatory support in cardiovascular/metabolic diseases; supporting early to late-stage clinical programs; matrixed biotech/pharma environment; emphasis on high-dimensional, multi-modal data integration. WorkSetup: not specified; implied collaborative, research-focused environment.