Associate Director, CMC Team Lead

Role: Associate Director, Downstream, Emerging Modalities, overseeing downstream process development for novel biologics, including antibodies and antibody-oligonucleotide conjugates (AOCs). Objectives: enable transition from preclinical to Phase I by designing scalable, robust purification strategies, and leading CMC activities. Responsibilities: lead downstream process design, optimize purification of complex modalities, collaborate with research, analytical, regulatory, and external partners, and support regulatory submissions with technical expertise. Qualifications: advanced degree in life sciences, chemical engineering, or related field; extensive experience in biologics or complex modalities, CMC leadership, and early-phase development; proven track record with emerging modalities like AOCs; strong cross-functional communication and project management skills. High-Value: biologics, antibody conjugates, AOCs, early development (preclinical to Phase I), CMC strategic leadership, regulatory interface, GMP oversight, process robustness, CDMO management. WorkSetup: onsite in Cambridge, MA.