Associate Director, Clinical Science (Autoimmune)
Xencor
June 25, 2026
Remote friendly (Pasadena, CA)
United States
Clinical Research and Development
Summary:
Responsible for facilitating successful and timely initiation and completion of clinical development programs in Inflammatory Bowel Disease (IBD) and other autoimmune programs by executing and monitoring medical aspects of selected global clinical trials, including randomized, placebo-controlled studies in IBD and studies in healthy volunteers.
Primary Responsibilities:
- Create clinical trial documents (protocols, investigator brochures, DSURs, IND clinical modules) with Study Medical Directors.
- Partner with Clinical Operations to execute trials with high quality and on timelines.
- Review clinical data; generate/resolution of queries; support data analysis and draft listing review.
- Provide scientific expertise during study conduct; clarify issues for Clinical Operations.
- Perform internal safety monitoring with the Study Medical Director.
- Contribute medical input to database build, CRFs, monitoring plan, data/safety monitoring plans, and SAP.
- Develop relationships with investigators and therapeutic area key opinion leaders.
- Lead review of study data and develop CSRs, clinical presentations, and publications.
- Support Clinical Development and Regulatory Affairs; participate on multidiscipline project teams.
Qualifications/Experience:
- BS in life sciences (PhD, RN, PharmD, or MS preferred).
- 10+ years directly relevant pharmaceutical industry clinical development experience.
- 2+ years experience focused in assigned therapeutic area.
- Clinical scientist experience in data review, safety monitoring, protocol development, data analysis, interpretation, and publications; IBD randomized, placebo-controlled clinical research experience.
- Preferred: translational medicine/early phase trials; monoclonal antibody biologics/immunotherapy; full study lifecycle experience (concept through database lock and CSR).
Skills (required):
- Strong initiative, organization, hands-on approach, attention to detail.
- Ability to analyze/interpret emerging clinical data; proficiency with EDC and tools (e.g., MS Office, Visio, GraphPad Prism, Spotfire, Medidata RAVE).
- Independent, able to prioritize multiple tasks; excellent communication.
Benefits/Compensation (as stated):
- Expected base salary range: $170,500–$208,500.
- Total rewards incl. 401k match, healthcare coverage, ESPP; annual bonus and equity grant.
Application:
See https://xencor.com/careers/.
Responsible for facilitating successful and timely initiation and completion of clinical development programs in Inflammatory Bowel Disease (IBD) and other autoimmune programs by executing and monitoring medical aspects of selected global clinical trials, including randomized, placebo-controlled studies in IBD and studies in healthy volunteers.
Primary Responsibilities:
- Create clinical trial documents (protocols, investigator brochures, DSURs, IND clinical modules) with Study Medical Directors.
- Partner with Clinical Operations to execute trials with high quality and on timelines.
- Review clinical data; generate/resolution of queries; support data analysis and draft listing review.
- Provide scientific expertise during study conduct; clarify issues for Clinical Operations.
- Perform internal safety monitoring with the Study Medical Director.
- Contribute medical input to database build, CRFs, monitoring plan, data/safety monitoring plans, and SAP.
- Develop relationships with investigators and therapeutic area key opinion leaders.
- Lead review of study data and develop CSRs, clinical presentations, and publications.
- Support Clinical Development and Regulatory Affairs; participate on multidiscipline project teams.
Qualifications/Experience:
- BS in life sciences (PhD, RN, PharmD, or MS preferred).
- 10+ years directly relevant pharmaceutical industry clinical development experience.
- 2+ years experience focused in assigned therapeutic area.
- Clinical scientist experience in data review, safety monitoring, protocol development, data analysis, interpretation, and publications; IBD randomized, placebo-controlled clinical research experience.
- Preferred: translational medicine/early phase trials; monoclonal antibody biologics/immunotherapy; full study lifecycle experience (concept through database lock and CSR).
Skills (required):
- Strong initiative, organization, hands-on approach, attention to detail.
- Ability to analyze/interpret emerging clinical data; proficiency with EDC and tools (e.g., MS Office, Visio, GraphPad Prism, Spotfire, Medidata RAVE).
- Independent, able to prioritize multiple tasks; excellent communication.
Benefits/Compensation (as stated):
- Expected base salary range: $170,500–$208,500.
- Total rewards incl. 401k match, healthcare coverage, ESPP; annual bonus and equity grant.
Application:
See https://xencor.com/careers/.