Associate Director, Clinical and Translational Imaging
NovartisWant to see how your resume matches up to this job? A free trial of our JobsAI will help! With over 2,000 biopharma executives loving it, we think you will too! Try it now — JobsAI.
Role Summary
The Biomarker Development (BMD) group at the Novartis Institutes for BioMedical Research (NIBR) is seeking a Senior Expert Imaging to join our Clinical Imaging team and actively provide strategic, scientific, technical and operational leadership on the optimal use of imaging in drug development. You will interact with clinical trial teams to establish the role of imaging endpoints along novel biological mechanisms across diverse therapeutic areas, spanning from research to early development and into P2-3 trials. The role provides exposure to additional biomarkers for an integrated view of identifying patient populations and novel readouts of efficacy and safety.
Responsibilities
- Act as an internal expert in PET/SPECT and Molecular Imaging with focus on clinical trials
- Partner with Oncology and General Medicine teams to develop and lead “fit for purpose” imaging strategy and execute on it
- Implement imaging in clinical trials to add insights on patient eligibility, efficacy, safety, and mechanism of action
- Collaborate and execute imaging readouts with internal operational support and external contract research organizations (CRO)
- Ensure quality and timely execution of imaging trials to deliver drug development decisions; be agile and responsive to clinical teams during design, execution and interpretation
- Develop and manage network of external experts; synthesize inputs and customize for specific protocols
- Collaborate with Research teams to develop and lead translational imaging studies
- Drive molecular imaging and ligand development from late pre-clinic to clinic
- Identify and/or develop novel imaging techniques and endpoints and implement them into clinical settings
Qualifications
- PhD or MD or MD/PhD with 8+ years of experience in PET/SPECT Imaging in academia or industry including 3+ years in clinical drug development
- Deep technical knowledge of PET and/or SPECT as applied to clinical drug development
- Strong understanding of clinical trial design, endpoints statistics and clinical data flow; experience with protocol writing across line functions
- Experience in clinical Radioligand/Radiopharmaceutical Therapy (RLT/RPT) is a plus
- Experience with imaging of Glioblastoma and brain metastases is a plus
- Experience with PET/SPECT clinical neuroscience drug development is a plus
- Experience in Regulatory submission, FIH, Dosimetry and receptor occupancy of molecular ligands is a plus
- Understanding of sites, budgets, imaging CROs and multisite trials is a plus
- Demonstrated track record of innovative research across imaging modalities
- Proactive, self-motivated and able to work in a multidisciplinary team; understands organizational needs
- Ability to drive for results with a sense of urgency and accountability
- Comfort working in a matrixed, supportive organization; mentorship skills
- Proficiency in English with strong communication skills
Skills
- Pervasive expertise in PET/SPECT Imaging for clinical development
- Clinical trial design, data interpretation and cross-functional collaboration
- Project management and external vendor management
Education
- PhD or MD or MD/PhD (as described in Qualifications)