Assoc. Scientific Director, Pharmacometrics
Neurocrine Biosciences
June 24, 2026
Remote friendly (San Diego, CA)
United States
Clinical Research and Development
About the Role
The Associate Director, Pharmacometrics leads pharmacokinetic (PK) and pharmacodynamic (PD) modeling and simulation (M&S) efforts driving clinical development for Neurocrine’s small- and large-molecule programs. Provides strategic PK/PD methodology expertise, performs/oversees pharmacometric analyses, and communicates findings to cross-functional stakeholders. Contributes to the design and execution of the Clinical Pharmacology and Pharmacometrics Development Plan.
Your Contributions (include, But Are Not Limited To)
- Lead pharmacometrics tasks and serve as function lead for assigned clinical development program; recommend modeling/simulation strategy
- Independently conduct and report population PK, PK/PD, and exposure-response analyses to support dose selection, trial design, and regulatory submissions
- Oversee design and reporting of M&S analyses conducted by external CROs
- Contribute M&S sections for internal decision boards and regulatory documents/interactions
- Prepare posters, publications, and presentations in quantitative pharmacology/pharmacometrics
- Mentor colleagues and may direct critical projects
Requirements
- PhD, PharmD, or equivalent preferred (PK/PK-PD modeling and simulation focus) with 5+ years post degree in drug development OR MS with 8+ years Pharmaceutical/Biotech industry experience
- Expert knowledge of early and late-stage M&S
- In-depth knowledge of clinical drug development and Clinical Pharmacology regulatory submission components (IND/NDA)
- Proficient with NONMEM, R, and WinNonlin
- Strong communications, problem-solving, analytical thinking, influencing skills
- Leadership/mentoring skills; strong project management and ability to meet multiple deadlines
Additional skills
- Experience preparing NDA/MAA summaries of population modeling (highly beneficial)
- Ability to work in cross-functional, matrix environments
Benefits (as stated)
- Retirement savings plan (company match), paid vacation/holidays/personal days, paid caregiver/parental and medical leave; medical, prescription drug, dental, and vision coverage
- Annual bonus (target 30% of earned base salary) and eligibility for equity-based long-term incentive program
Annual base salary (as stated)
- $171,800.00–$235,000.00
The Associate Director, Pharmacometrics leads pharmacokinetic (PK) and pharmacodynamic (PD) modeling and simulation (M&S) efforts driving clinical development for Neurocrine’s small- and large-molecule programs. Provides strategic PK/PD methodology expertise, performs/oversees pharmacometric analyses, and communicates findings to cross-functional stakeholders. Contributes to the design and execution of the Clinical Pharmacology and Pharmacometrics Development Plan.
Your Contributions (include, But Are Not Limited To)
- Lead pharmacometrics tasks and serve as function lead for assigned clinical development program; recommend modeling/simulation strategy
- Independently conduct and report population PK, PK/PD, and exposure-response analyses to support dose selection, trial design, and regulatory submissions
- Oversee design and reporting of M&S analyses conducted by external CROs
- Contribute M&S sections for internal decision boards and regulatory documents/interactions
- Prepare posters, publications, and presentations in quantitative pharmacology/pharmacometrics
- Mentor colleagues and may direct critical projects
Requirements
- PhD, PharmD, or equivalent preferred (PK/PK-PD modeling and simulation focus) with 5+ years post degree in drug development OR MS with 8+ years Pharmaceutical/Biotech industry experience
- Expert knowledge of early and late-stage M&S
- In-depth knowledge of clinical drug development and Clinical Pharmacology regulatory submission components (IND/NDA)
- Proficient with NONMEM, R, and WinNonlin
- Strong communications, problem-solving, analytical thinking, influencing skills
- Leadership/mentoring skills; strong project management and ability to meet multiple deadlines
Additional skills
- Experience preparing NDA/MAA summaries of population modeling (highly beneficial)
- Ability to work in cross-functional, matrix environments
Benefits (as stated)
- Retirement savings plan (company match), paid vacation/holidays/personal days, paid caregiver/parental and medical leave; medical, prescription drug, dental, and vision coverage
- Annual bonus (target 30% of earned base salary) and eligibility for equity-based long-term incentive program
Annual base salary (as stated)
- $171,800.00–$235,000.00