Assoc Prin. Scientist, Analytical R&D

Role Summary

The Materials & Biophysical Characterization (MBC) group within Analytical Research & Development seeks a highly motivated materials scientist to impact our pipeline from discovery through development and commercial launch. This role focuses on physicochemical characterization of pharmaceutical materials including small molecule active pharmaceutical ingredients (API), chemical intermediates, peptides, novel excipients, drug-product intermediates, and drug products. The candidate will apply expertise in physical organic chemistry or materials science on cross-functional teams to address crystallization, polymorph and salt-selection, drug-excipient compatibility, and amorphous solid dispersions, as well as physical stability of APIs and drug products. The position emphasizes collaboration across Discovery Chemistry, Process & Analytical Chemistry, Chemical Engineering, and Formulations Sciences, and contributes to a culture of scientific excellence and compliance.

Responsibilities

• Characterize pharmaceutical materials using techniques such as X-ray diffraction, thermal analysis, electron microscopy, vibrational spectroscopy, particle size analysis, and powder property characterization.
• Address crystallization, polymorph and salt-selection, drug-excipient compatibility, amorphous solid dispersion characterization, and physical stability of APIs and drug products as part of cross-functional teams.
• Collaborate with internal and external partners across Discovery Chemistry, Process & Analytical Chemistry, Chemical Engineering, and Formulations Sciences; contribute to scientific excellence and regulatory compliance.

Qualifications

• Required: Expertise in materials science or physical chemistry with experience in materials characterization techniques such as X-ray diffraction, thermal analysis, electron microscopy, vibrational spectroscopy, particle size analysis or powder property characterization.
• Required: Strong academic record including publications in peer reviewed journals and presentations at scientific meetings.
• Required: Self-motivated, creative and energetic scientist willing to continually learn and solve complex problems.
• Required: Strong written and verbal communications.
• Preferred: Experience with at least one of the following: API polymorph screening and crystallization; Amorphous solid dispersion characterization; Modified release dosage forms; Rheological characterization of complex fluids or suspensions; Late-stage product development and regulatory documentation / filing.

Skills

• Accountability
• Adaptability
• Analytical Chemistry
• Analytical Method Development
• Assay Development
• Biological Assay Development
• Cell-Based Assays
• Chemical Analysis
• Chemical Biology
• Chemical Engineering
• Chemical Physics
• Chromatographic Techniques
• Communication
• Cross-Functional Teamwork
• Crystallizations
• External Collaboration
• High Resolution Mass Spectrometry (HRMS)
• Liquid Chromatography-Mass Spectrometry (LC-MS)
• Mass Spectrometry Analysis
• Materials Engineering
• Materials Science
• Optimistic Attitude
• Oral Communications
• Organic Chemistry

Education

• Bachelors or Masters degree in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline, with a minimum of eight (8) years relevant industrial experience (non-academic).
• PhD in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 4 years relevant industrial experience (non-academic).

Additional Requirements

• Travel: 10%