Advisor – Process Engineer. Lilly Medicine Foundry
Eli Lilly and Company
August 24, 2026
On-site
Lebanon, IN
$129,000 - $189,200 USD yearly
Operations
Responsibilities:
- Serve as technical authority for equipment design and scale-up calculations across small-molecule node; lead engineering calculations (heat/mass transfer modeling, equipment sizing).
- Conduct rig-fit assessments using process simulation tools (e.g., DynoChem, Aspen) for scale-up to kilo lab/pilot.
- Provide reactor system guidance for batch/semi-batch, continuous flow, hydrogenation, SPPS peptide synthesis, and oligonucleotide synthesis.
- Drive scale-up to pilot plant; ensure heat/mass transfer, mixing, and process safety are evaluated/documented at each scale transition.
- Lead P&ID reviews; translate development-scale chemistry into fit-for-purpose equipment specs and control strategies.
- Support preparation of IND/CTX and regulatory submissions; author technical reports/basis-of-design/specs; maintain records.
- Lead compliance and safety (incl. Process Hazard Reviews/HAZOPs) and mentor/train process engineers; manage short- and long-term engineering development and projects.
Basic Qualifications:
- PhD in Chemical Engineering/Chemistry/Pharmaceutical Sciences (or related), OR BS/MS in Chemical Engineering (or related) with 10+ years in pharma/biotech/CMO process engineering for drug-substance API development/manufacturing.
Additional Skills/Preferences:
- Expertise in reaction chemistry, crystallization, extraction, distillation, and small-molecule API unit operations; project management; leadership and collaboration.
- Excellent written/verbal communication; persuasion/influence/negotiation.
- Preferred: SMDD (or equivalent) experience; cGMP pilot/clinical manufacturing support; experience with DynoChem/Aspen and DeltaV.
Other:
- Limited travel (<10%); work in 24-hour manufacturing/lab environments.
- Location: Parkwood West (initial), permanent at Lilly Medicine Foundry, Lebanon, IN.
- Anticipated base pay: $129,000–$189,200; eligible for company bonus and comprehensive benefits (401(k), medical/dental/vision, life insurance, vacation/leave, well-being).
- Serve as technical authority for equipment design and scale-up calculations across small-molecule node; lead engineering calculations (heat/mass transfer modeling, equipment sizing).
- Conduct rig-fit assessments using process simulation tools (e.g., DynoChem, Aspen) for scale-up to kilo lab/pilot.
- Provide reactor system guidance for batch/semi-batch, continuous flow, hydrogenation, SPPS peptide synthesis, and oligonucleotide synthesis.
- Drive scale-up to pilot plant; ensure heat/mass transfer, mixing, and process safety are evaluated/documented at each scale transition.
- Lead P&ID reviews; translate development-scale chemistry into fit-for-purpose equipment specs and control strategies.
- Support preparation of IND/CTX and regulatory submissions; author technical reports/basis-of-design/specs; maintain records.
- Lead compliance and safety (incl. Process Hazard Reviews/HAZOPs) and mentor/train process engineers; manage short- and long-term engineering development and projects.
Basic Qualifications:
- PhD in Chemical Engineering/Chemistry/Pharmaceutical Sciences (or related), OR BS/MS in Chemical Engineering (or related) with 10+ years in pharma/biotech/CMO process engineering for drug-substance API development/manufacturing.
Additional Skills/Preferences:
- Expertise in reaction chemistry, crystallization, extraction, distillation, and small-molecule API unit operations; project management; leadership and collaboration.
- Excellent written/verbal communication; persuasion/influence/negotiation.
- Preferred: SMDD (or equivalent) experience; cGMP pilot/clinical manufacturing support; experience with DynoChem/Aspen and DeltaV.
Other:
- Limited travel (<10%); work in 24-hour manufacturing/lab environments.
- Location: Parkwood West (initial), permanent at Lilly Medicine Foundry, Lebanon, IN.
- Anticipated base pay: $129,000–$189,200; eligible for company bonus and comprehensive benefits (401(k), medical/dental/vision, life insurance, vacation/leave, well-being).