ADME Project Leadership for Genetic Medicines

Role: ADME / DMPK scientist specializing in genetic medicines, supporting preclinical and clinical development at Lilly’s Boston campus. Responsibilities: lead ADME studies, integrate PK/PD data with chemistry and biology findings to optimize drug design, interpret hypothesis-driven experiments, collaborate with cross-functional teams, and prepare regulatory submissions. Requirements: Ph.D. in Biochemistry, Pharmacology, or related fields; 5+ years in pharmaceutical/biotech ADME/PK/PD roles; strong knowledge of pharmacokinetics, ADME principles, and bioanalytical methods. Preferred: experience with gene editing, gene therapy, biodistribution of oligonucleotides, PK/PD modeling, and regulatory documents. High-value specifics: focus on genetic modalities such as gene editing, gene therapy, siRNAs, ASOs; involvement in preclinical and clinical phases; interaction with global regulatory agencies. Work setup: full-time, based in Boston MA, no explicit travel requirements.